Prevalence of Uropathogen and their Antimicrobial Resistance Pattern in a Tertiary Care Teaching Hospital in Port Blair, India

Introduction: Urinary tract infection (UTI) is one of the most common infections seen in the community. Knowledge of common uropathogen and their antimicrobial susceptibility is necessary for initiation of empirical therapy. This study aimed to determine the spectrum of organisms responsible for UTI and their antimicrobial susceptibility pattern in a Medical College Hospital situated in an Island in the Bay of Bengal. Material and Methods: Urine samples received in Microbiology Laboratory between April 2015 to March 2016 were processed according to standard guidelines. The antimicrobial susceptibility testing was performed by the Kirby-Bauer’s disc diffusion method and interpreted as per CLSI guidelines. Results: Total of 7850 urine samples were processed during the study period, 956 (12.18%) had significant bacterial growth, of which 65.27% belonged to women and 34.73% to men. Gram negative bacteria (GNB) were isolated in74.79% followed by Gram Positive bacteria 20.40% and yeast 4.81% isolates. The commonest uropathogen was Escherichia coli (48.01%). The uropathogens were most resistant to Ampicillin (91.5%), while they were highly sensitive to Levofloxacin and Meropenem. The GPCs were most resistant to Penicillin (66.67%). Conclusion: Uropathogens were most commonly isolated in 15-30 years age group and the most common isolated microorganism was Escherichia coli. Regular prevalence studies on uropathogens is warranted to assess the trends of the ever changing scenario.